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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human spleen tissue and Human lung tissue lysates, Primary antibody: P09500(CHIT1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P09500(CHIT1 Antibody) at dilution 1/30. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P09500(CHIT1 Antibody) at dilution 1/30. (Original magnification: ×200)

Rabbit Polyclonal Antibody to CHIT1

货号：
P09500
别名：
CHI3; CHIT; CHITD
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13231
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to CHIT1

Description
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Description

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Specification
Aliases	CHI3; CHIT; CHITD
Swissprot	Q13231
WB Predicted band size	52 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human CHIT1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.