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Rabbit Polyclonal Antibody to ZYX
-
货号:
P09255 -
别名:
ESP-2; HED-2 -
应用:
WB,IHC -
反应种属:
Human, Mouse -
抗体类型:
Primary antibody -
Swissprot:
Q15942 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to ZYX
Description |
---|
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. |
Specification |
|
---|---|
Aliases | ESP-2; HED-2 |
Swissprot | Q15942 |
WB Predicted band size | 61 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human ZYX |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
---|---|
WB | 1/200-1/1000 |
IHC | 1/25-1/100 |
ELISA | 1/5000-1/10000 |
Product Image
- Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 293T cell lysate, Primary antibody: P09255(ZYX Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
- The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P09255(ZYX Antibody) at dilution 1/30. (Original magnification: ×200)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P09255

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