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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human heart tissue lysate, Primary antibody: P09141(TNNC1 Antibody) at dilution 1/750, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds

The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P09141(TNNC1 Antibody) at dilution 1/100. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to TNNC1

货号：
P09141
别名：
TNC; TN-C; TNNC; CMD1Z; CMH13
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
P63316
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to TNNC1

Description
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Description

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Specification
Aliases	TNC; TN-C; TNNC; CMD1Z; CMH13
Swissprot	P63316
WB Predicted band size	18 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human TNNC1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.