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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse fat tissue lysate, Primary antibody: P09015(ZFAND5 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09015(ZFAND5 Antibody) at dilution 1/35. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P09015(ZFAND5 Antibody) at dilution 1/35. (Original magnification: ×200)

Rabbit Polyclonal Antibody to ZFAND5

货号：
P09015
别名：
ZA20D2; ZNF216; ZFAND5A
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
O76080
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to ZFAND5

Description
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Description

Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Specification
Aliases	ZA20D2; ZNF216; ZFAND5A
Swissprot	O76080
WB Predicted band size	23 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Full length fusion protein
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.