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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human bladder carcinoma and fetal liver tissue, Primary antibody: P08986(VPS37A Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08986(VPS37A Antibody) at dilution 1/30. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08986(VPS37A Antibody) at dilution 1/30. (Original magnification: ×200)

Rabbit Polyclonal Antibody to VPS37A

货号：
P08986
别名：
HCRP1; PQBP2; SPG53
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q8NEZ2
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to VPS37A

Description
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Description

This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Specification
Aliases	HCRP1; PQBP2; SPG53
Swissprot	Q8NEZ2
WB Predicted band size	44 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human VPS37A
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.