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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-5: K562 cells, hepg2 cells, 231 cells, Jurkat cells, Raji cells, Primary antibody: P08656(PTRH2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P08656(PTRH2 Antibody) at dilution 1/20. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P08656(PTRH2 Antibody) at dilution 1/20. (Original magnification: ×200)

Rabbit Polyclonal Antibody to PTRH2

货号：
P08656
别名：
BIT1; PTH2; CFAP37; CGI-147
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q9Y3E5
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to PTRH2

Description
PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.

Description

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.

Specification
Aliases	BIT1; PTH2; CFAP37; CGI-147
Swissprot	Q9Y3E5
WB Predicted band size	19 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human PTRH2
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.