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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Raw264.7 cells, Primary antibody: P08496(TAB3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08496(TAB3 Antibody) at dilution 1/35. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to TAB3

货号：
P08496
别名：
NAP1; MAP3K7IP3
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q8N5C8
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to TAB3

Description
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Description

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Specification
Aliases	NAP1; MAP3K7IP3
Swissprot	Q8N5C8
WB Predicted band size	79 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human TAB3
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.