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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cell lysate and Human fetal liver tissue lysate, Primary antibody: P08417(AKR1C4 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08417(AKR1C4 Antibody) at dilution 1/25. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to AKR1C4

货号：
P08417
别名：
C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P17516
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to AKR1C4

Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Specification
Aliases	C11; CDR; DD4; CHDR; DD-4; HAKRA; 3-alpha-HSD
Swissprot	P17516
WB Predicted band size	37 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Full length fusion protein
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.