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The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P08168(CFL1 Antibody) at dilution 1/30. (Original magnification: ×200)

Rabbit Polyclonal Antibody to CFL1

  • 货号:

    P08168
  • 别名:

    CFL
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P23528
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to CFL1

Description

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Specification

Aliases CFL
Swissprot P23528
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human CFL1
Formulation Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

IHC 1/50-1/200
ELISA 1/2000-1/5000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P08168