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Gel: 8%SDS-PAGE, Lysate: 20 μg, Lane: Human fetal brain tissue, Primary antibody: P07998(GPM6A Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second

The image is immunohistochemistry of paraffin-embedded Human brain tissue using P07998(GPM6A Antibody) at dilution 1/50. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07998(GPM6A Antibody) at dilution 1/50. (Original magnification: ×200)

Rabbit Polyclonal Antibody to GPM6A

货号：
P07998
别名：
M6A; GPM6
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P51674
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to GPM6A

Description
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Description

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Specification
Aliases	M6A; GPM6
Swissprot	P51674
WB Predicted band size	31 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human GPM6A
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.