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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji cells, huvec cells, Primary antibody: P07991(ICAM1 Antibody) at dilution 1/1150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second

The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P07991(ICAM1 Antibody) at dilution 1/50. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07991(ICAM1 Antibody) at dilution 1/50. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to ICAM1

货号：
P07991
别名：
BB2; CD54; P3.58
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P05362
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to ICAM1

Description
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Description

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Specification
Aliases	BB2; CD54; P3.58
Swissprot	P05362
WB Predicted band size	58 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human ICAM1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.