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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cell lysate, Primary antibody: P07537(EIF2AK3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07537(EIF2AK3 Antibody) at dilution 1/60. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P07537(EIF2AK3 Antibody) at dilution 1/60. (Original magnification: ×200)

Rabbit Polyclonal Antibody to EIF2AK3

货号：
P07537
别名：
PEK; WRS; PERK
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q9NZJ5
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to EIF2AK3

Description
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Description

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Specification
Aliases	PEK; WRS; PERK
Swissprot	Q9NZJ5
WB Predicted band size	125 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human EIF2AK3
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.