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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: 293T cells, A549 cells, Raji cells, K562 cells, NIH/3T3 cells, Primary antibody: P07441(MCM6 Antibody) at dilution 1/433.3, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07441(MCM6 Antibody) at dilution 1/60. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07441(MCM6 Antibody) at dilution 1/60. (Original magnification: ×200)

Rabbit Polyclonal Antibody to MCM6

货号：
P07441
别名：
Mis5; P105MCM; MCG40308
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q14566
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to MCM6

Description
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Specification
Aliases	Mis5; P105MCM; MCG40308
Swissprot	Q14566
WB Predicted band size	93 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human MCM6
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.