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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P00969(DNMT3A Antibody) at dilution 1/50. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00969(DNMT3A Antibody) at dilution 1/50. (Original magnification: ×200)

Rabbit Polyclonal Antibody to DNMT3A

货号：
P00969
别名：
DNMT3A2; M.HsaIIIA
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q9Y6K1
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to DNMT3A

Description
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Description

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specification
Aliases	DNMT3A2; M.HsaIIIA
Swissprot	Q9Y6K1
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human DNMT3A
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.