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Gel: 10%SDS-PAGE, Lysate: 50 μg, Lane 1-2: Hela cells, 231 cells, Primary antibody: P00646(RRM1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P00646(RRM1 Antibody) at dilution 1/15. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P00646(RRM1 Antibody) at dilution 1/15. (Original magnification: ×200)

Rabbit Polyclonal Antibody to RRM1

货号：
P00646
别名：
R1; RR1; RIR1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
P23921
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to RRM1

Description
This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Description

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Specification
Aliases	R1; RR1; RIR1
Swissprot	P23921
WB Predicted band size	90 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human RRM1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.