Rabbit Monoclonal to Nck2

Description
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.

Specification
Aliases	GRB4; NCK adaptor protein 2; NCK2; NCKbeta;;NCK2
Swissprot	O43639
WB Predicted band size	Calculated MW: 43 kDa ; Observed MW: 47 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human NCK2
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF	1/50-1/200