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Rabbit Monoclonal to PEN2
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货号:
P18594 -
别名:
PEN 2; PSEN2; psenen;;PEN 2 -
应用:
WB,IHC/IHF,IF,FCM -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q9NZ42 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to PEN2
Description |
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Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity. |
Specification |
|
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Aliases | PEN 2; PSEN2; psenen;;PEN 2 |
Swissprot | Q9NZ42 |
WB Predicted band size | Calculated MW: 12 kDa ; Observed MW: 13 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human PEN 2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P18594

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