提醒成功

搜索
Rabbit Monoclonal to GPCR/LGR6
-
货号:
P18472 -
别名:
GPCR; Lgr6;;LGR6 -
应用:
WB,IHC/IHF,IF,FCM -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q9HBX8 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to GPCR/LGR6
Description |
---|
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. |
Specification |
|
---|---|
Aliases | GPCR; Lgr6;;LGR6 |
Swissprot | Q9HBX8 |
WB Predicted band size | 104 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human LGR6 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P18472

相关产品


