Rabbit Monoclonal to TAB1

Description
Key adapter protein that plays an essential role in JNK and NF-kappa-B activation and proinflammatory cytokines production in response to stimulation with TLRs and cytokines.Mechanistically, associates with the catalytic domain of MAP3K7/TAK1 to trigger MAP3K7/TAK1 autophosphorylation leading to its full activation.

Specification
Aliases	MAP3K7IP1; TAB1; TAK1 binding protein 1;;TAB1
Swissprot	Q15750
WB Predicted band size	55 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human TAB1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IP	1/20-1/50
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF	1/50-1/200
FCM	1/20-1/100