Rabbit Monoclonal to Nicastrin

Description
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.

Specification
Aliases	APH2; Ncstn; NCT; Nicastrin;;Nicastrin
Swissprot	Q92542
WB Predicted band size	Calculated MW: 78 kDa ; Observed MW: 120,140 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human Nicastrin
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IF/ICC	1/50-1/200