Rabbit Monoclonal to MAD1

Description
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate.Forms a heterotetrameric complex with the closed conformation form of MAD2L1 (C-MAD2) at unattached kinetochores during prometaphase, recruits an open conformation of MAD2L1.

Specification
Aliases	hMAD1; HsMAD1; MAD1; MAD1L1; PIG9; TP53I9; TXBP181;;MAD1
Swissprot	Q9Y6D9
WB Predicted band size	Calculated MW: 83 kDa ; Observed MW: 80 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human MAD1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000