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All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Western blot analysis of CRM1 expression in HeLa cell lysate.
HOT

Rabbit Monoclonal to CRM1

  • 货号:

    P18158
  • 别名:

    CRM 1; emb; Exp1; Exportin1; XPO 1;;Exportin 1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC/IHF,IF,FCM
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O14980
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal to CRM1

Description

Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.

Specification

Aliases CRM 1; emb; Exp1; Exportin1; XPO 1;;Exportin 1
Swissprot O14980
WB Predicted band size Calculated MW: 123 kDa ; Observed MW: 110 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Exportin 1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200
FCM 1/20-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P18158