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Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cell lysate, Primary antibody: P00543(MSH3 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds

The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P00543(MSH3 Antibody) at dilution 1/85. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P00543(MSH3 Antibody) at dilution 1/85. (Original magnification: ×200)

Rabbit Polyclonal Antibody to MSH3

货号：
P00543
别名：
DUP; FAP4; MRP1
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
P20585
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to MSH3

Description
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

Description

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

Specification
Aliases	DUP; FAP4; MRP1
Swissprot	P20585
WB Predicted band size	127 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human MSH3
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.