Rabbit Monoclonal to Presenilin 1

Description
Requires the presence of the other members of the gamma-secretase complex for protease activity.Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

Specification
Aliases	AD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182;;Presenilin 1
Swissprot	P49768
WB Predicted band size	Calculated MW: 53 kDa ; Observed MW: 28 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Presenilin 1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
FCM	1/20-1/100