Rabbit Monoclonal to Homer 1

Description
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2.

Specification
Aliases	Homer; HOMER 1A; HOMER 1B; HOMER 1C; homer homolog 1; Homer1; HOMER1A; HOMER1B; HOMER1C; SYN47;;Homer 1
Swissprot	Q86YM7
WB Predicted band size	Calculated MW: 40 kDa ; Observed MW: 45 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Homer 1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IP	1/20-1/50
IHC	1/100-1/200