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Western blot analysis of GNE expression in K562 cell lysate.
Rabbit Monoclonal to GNE
-
货号：
P17887 -
别名：
DMRV; GNE; IBM2; ManAc kinase; Uae1;;GNE -
应用：
WB,IF -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q9Y223 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Monoclonal to GNE
Description |
|---|
Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation. |
Specification |
|
|---|---|
| Aliases | DMRV; GNE; IBM2; ManAc kinase; Uae1;;GNE |
| Swissprot | Q9Y223 |
| WB Predicted band size | Calculated MW: 79 kDa ; Observed MW: 75 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human GNE |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IF | 1/50-1/200 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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