Rabbit Monoclonal to Klotho

Description
May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D.

Specification
Aliases	Kl; Klotho peptide;;Klotho
Swissprot	Q9UEF7
WB Predicted band size	Calculated MW: 116 kDa ; Observed MW: 62 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthesized peptide derived from human Klotho
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IHC	1/100-1/200