Rabbit Monoclonal to macroH2A.1

Description
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription.Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

Specification
Aliases	H2A.y; H2A/y; H2AF12M; H2AFJ; H2afy; Histone H2A.Y; Histone macroH2A1; Histone macroH2A1.1; Histone macroH2A1.2; mH2a;mH2A1;;Histone mH2A1
Swissprot	O75367
WB Predicted band size	40 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Histone mH2A1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF/ICC	1/50-1/200