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Western blot analysis of FADD expression in Raw264.7 cell lysate.

Rabbit Monoclonal to FADD

  • 货号:

    P17787
  • 别名:

    FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1;;Fadd
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB;IHC;FCM
  • 反应种属:

    Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q61160(mouse)(human:Q13158)
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal to FADD

Description

Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

Specification

Aliases FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1;;Fadd
Swissprot Q61160(mouse)(human:Q13158)
WB Predicted band size Calculated MW: 23 kDa ; Observed MW: 28 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen A synthesized peptide derived from mouse Fadd
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC 1/100-1/200
FCM 1/20-1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P17787