Rabbit Monoclonal to PIAS1+PIAS2

Description
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.

Specification
Aliases	PIAS1; PIAS2;;PIAS1/2
Swissprot	O75925/O75928
WB Predicted band size	Calculated MW: 72,68 kDa ; Observed MW: 76 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human PIAS1
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IP	1/20-1/50
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF	1/50-1/200
FCM	1/20-1/100