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Western blot analysis of ASPP2 expression in MCF7 cell lysate.
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.

Rabbit Monoclonal to ASPP2

  • 货号:

    P17502
  • 别名:

    53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2;;TP53BP2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC/IHF,IF,
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13625
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal to ASPP2

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specification

Aliases 53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2;;TP53BP2
Swissprot Q13625
WB Predicted band size Calculated MW: 126 kDa ; Observed MW: 150 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthesized peptide derived from human TP53BP2
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P17502