Rabbit Monoclonal to Argonaute 2

Description
Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing.

Specification
Aliases	Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD; ;Argonaute 2
Swissprot	Q9UKV8
WB Predicted band size	97 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Argonaute 2
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IP	1/20-1/50
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF	1/50-1/200
FCM	1/20-1/100