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Western blot analysis of STAT2 expression in K562 cell lysate.
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
Immunofluorescent analysis of A431 cells, using STAT2 Antibody.
Immunohistochemical analysis of paraffin-embedded human lung cancer, using STAT2 Antibody.
HOT

Rabbit Monoclonal to STAT2

  • 货号:

    P17387
  • 别名:

    Homo sapiens interferon alpha induced transcriptional activator; ISGF 3; P113; signal transducer and activator of transcription 2 113kD; STAT113; Stat2;;STAT2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC/IHF,IF,
  • 反应种属:

    Human,Mouse,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P52630
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal to STAT2

Description

Signal transducer and activator of transcription that mediates signaling by type I interferons (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Specification

Aliases Homo sapiens interferon alpha induced transcriptional activator; ISGF 3; P113; signal transducer and activator of transcription 2 113kD; STAT113; Stat2;;STAT2
Swissprot P52630
WB Predicted band size Calculated MW: 98 kDa ; Observed MW: 97 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human STAT2
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IHC IHC:1/100-1/200;IHF:1/50-1/200
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P17387