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Rabbit Monoclonal to STAT2
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货号:
P17387 -
别名:
Homo sapiens interferon alpha induced transcriptional activator; ISGF 3; P113; signal transducer and activator of transcription 2 113kD; STAT113; Stat2;;STAT2 -
应用:
WB,IHC/IHF,IF, -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P52630 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to STAT2
Description |
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Signal transducer and activator of transcription that mediates signaling by type I interferons (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
Specification |
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Aliases | Homo sapiens interferon alpha induced transcriptional activator; ISGF 3; P113; signal transducer and activator of transcription 2 113kD; STAT113; Stat2;;STAT2 |
Swissprot | P52630 |
WB Predicted band size | Calculated MW: 98 kDa ; Observed MW: 97 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human STAT2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P17387

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