Rabbit Monoclonal to Lin 28B

Description
Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c. Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA.

Specification
Aliases	CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B;;Lin 28B
Swissprot	Q6ZN17
WB Predicted band size	Calculated MW: 27 kDa ; Observed MW: 30 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human Lin 28B
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IP	1/20-1/50
IF/ICC	1/50-1/200
FCM	1/20-1/100