Rabbit Monoclonal to Phospho-HistoneH1.4(T17)

Description
Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.

Specification
Aliases	Histone H1b; Histone H1s-4;;p-Histone H1.4 (T17)
Swissprot	P10412/P16402
WB Predicted band size	Calculated MW: 22 kDa ; Observed MW: 30 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthesized peptide derived from human Histone H1.4 around the phosphorylation site of T17
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000
IHC	IHC:1/100-1/200;IHF:1/50-1/200
IF/ICC	1/50-1/200