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Rabbit Monoclonal to ERK1/2
-
货号:
P17216 -
别名:
ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,;ERK1/2 -
应用:
WB,IF,IP,FCM -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P27361/P28482 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to ERK1/2
Description |
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Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. |
Specification |
|
---|---|
Aliases | ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,;ERK1/2 |
Swissprot | P27361/P28482 |
WB Predicted band size | Calculated MW: 43,41 kDa ; Observed MW: 42,44 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human ERK1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IP | 1/20-1/50 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |
Product Image
- All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
- All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
- All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
- Polysaccharides from Nostoc commune Vaucher activate macrophages via NF-κB and AKT/JNK1/2 pathways to suppress colorectal cancer growth in vivo. -Food & Function
- Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. -Oncology Reports
- CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. -Molecular Cancer
- Immunofluorescent analysis of Hela cells, using ERK1/2 Antibody.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P17216

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