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Rabbit Monoclonal to CXCR4
-
货号:
P17149 -
别名:
CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;;CXCR4 -
应用:
WB,IHC/IHF,IF, -
反应种属:
Human,Mouse -
抗体类型:
Primary antibody -
Swissprot:
P61073 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to CXCR4
Description |
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Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. |
Specification |
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Aliases | CD184 ; CXCR4; C-X-C chemokine receptor type 4; FB22; Fusin; HM89; LCR1; LESTR; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor;;CXCR4 |
Swissprot | P61073 |
WB Predicted band size | Calculated MW: 40 kDa ; Observed MW: 43 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | A synthesized peptide derived from human CXCR4 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
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WB | 1/500-1/1000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
Product Image
- All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
- All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
- All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.
- Immunofluorescent analysis using the Antibody at 1:50 dilution.
- Immunofluorescent analysis of Jurkat cells, using CXCR4 Antibody .
- Immunohistochemical analysis of paraffin-embedded human cervical carcinoma, using CXCR4 Antibody.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P17149

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