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Rabbit Monoclonal to DAPKinase1
-
货号:
P17115 -
别名:
DAK1; DAP K1; DAP kinase 1; DAPK 1; DAPK; DAPK1; DAPK1_HUMAN; Death Associated Protein Kinase 1; Death-associated protein kinase 1;;DAP kinase 1 -
应用:
WB,IHC/IHF,IF, -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P53355 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal to DAPKinase1
Description |
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Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. Phosphorylates TPM1, enhancing stress fiber formation in endothelial cells. Phosphorylates STX1A and significantly decreases its binding to STXBP1. |
Specification |
|
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Aliases | DAK1; DAP K1; DAP kinase 1; DAPK 1; DAPK; DAPK1; DAPK1_HUMAN; Death Associated Protein Kinase 1; Death-associated protein kinase 1;;DAP kinase 1 |
Swissprot | P53355 |
WB Predicted band size | 160 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthesized peptide derived from human DAP kinase 1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/1000-1/2000 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
Product Image
- Western blot analysis of DAP Kinase 1 expression in HeLa cell lysate.
- All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.
- Immunofluorescent analysis of Hela cells, using DAP Kinase 1 Antibody .
- Immunohistochemical analysis of paraffin-embedded human breast cancer, using DAP Kinase 1 Antibody.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P17115

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