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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Phospho-MLKL (S345) expression in (1) L929 treated with Z-VAD + TNF alpha + SM164 cell lysate; (2) Untreated.

Rabbit Monoclonal to Phospho-MLKL(S345)

货号：
P17066
别名：
hMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase;;p-Mlkl (S345)
产品上架时间：
2024-01-01
应用：
WB;IP
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q9D2Y4(mouse)Q8NB16(Human)
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Description
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Does not have protein kinase activity.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

Specification
Aliases	hMLKL ; Mixed lineage kinase domain like; Mixed lineage kinase domain like protein; Mixed lineage kinase domain like pseudokinase;;p-Mlkl (S345)
Swissprot	Q9D2Y4(mouse)Q8NB16(Human)
WB Predicted band size	54 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	A synthesized peptide derived from mouse Mlkl around the phosphorylation site of S345
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.