Rabbit Monoclonal to Phospho-GCN2(T899)

Description
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.

Specification
Aliases	GCN2-like protein; GCN2; KIAA1338; EIF2AK4;;p-GCN2 (T899)
Swissprot	Q9P2K8
WB Predicted band size	Calculated MW: 187 kDa ; Observed MW: 220 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human GCN2 around the phosphorylation site of T899
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application
WB	1/1000-1/2000