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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Hela cells, A431 cells, 293T cells, Jurkat cells, Primary antibody: P00110(BAK1 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds

The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P00110(BAK1 Antibody) at dilution 1/50. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P00110(BAK1 Antibody) at dilution 1/50. (Original magnification: ×200)

Rabbit Polyclonal Antibody to BAK1

货号：
P00110
别名：
BAK; CDN1; BCL2L7; BAK-LIKE
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q16611
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to BAK1

Description
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Specification
Aliases	BAK; CDN1; BCL2L7; BAK-LIKE
Swissprot	Q16611
WB Predicted band size	23 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human BAK1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.