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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MYT1 (Phospho-Ser83) antibody P40448 (left)or the same antibody preincubated with blocking peptide (right).

Rabbit Polyclonal Antibody to MYT1 (Phospho-Ser83)

货号：
P40448
别名：
PMYT1; PKMYT1; MYT1 kinase;
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99640
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to MYT1 (Phospho-Ser83)

Description
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997)Liu F., Mol. Cell. Biol. 17:571-583(1997)Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006)

Description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997)Liu F., Mol. Cell. Biol. 17:571-583(1997)Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006)

Specification
Aliases	PMYT1; PKMYT1; MYT1 kinase;
Entrez GeneID	9088;
Swissprot	Q99640
WB Predicted band size	54kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.