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Western blot analysis of Phospho-lamban (Phospho-Ser16) in mouse heart lysates using Phospho-Phospho-lamban (Ser16) antibody.
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Rabbit Monoclonal Antibody to Phospho-Phospholamban (Ser16)

  • 货号:

    P20138
  • 别名:

    PLN; PLB; Cardiac phospholamban; PLB
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P26678
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Phospho-Phospholamban (Ser16)

Description

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.

Specification

Aliases PLN; PLB; Cardiac phospholamban; PLB
Entrez GeneID 5350
Swissprot P26678
WB Predicted band size Calculated MW: 6 kDa; Observed MW: 12,24 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser16 of human Phospholamban
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P20138