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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse heart tissue and K562 cell lysates, Primary antibody: P13369(ACOD1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

Rabbit Polyclonal Antibody to ACOD1

货号：
P13369
别名：
CAD; IRG1
产品上架时间：
2024-02-02
应用：
ELISA；WB
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
A6NK06
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to ACOD1

Description
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Description

Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Specification
Aliases	CAD; IRG1
Swissprot	A6NK06
WB Predicted band size	53 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human ACOD1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.