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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Human fetal brain tissue, PC-3, Hela and 293T cell lysates, Primary antibody: P13186(PNPO Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

The image is immunohistochemistry of paraffin-embedded Human brain tissue using P13186(PNPO Antibody) at dilution 1/30. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P13186(PNPO Antibody) at dilution 1/30. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to PNPO

货号：
P13186
别名：
PDXPO; HEL-S-302
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q9NVS9
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PNPO

Description
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Description

The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.

Specification
Aliases	PDXPO; HEL-S-302
Swissprot	Q9NVS9
WB Predicted band size	30 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human PNPO
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.