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The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P12975(ANAPC15 Antibody) at dilution 1/70. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P12975(ANAPC15 Antibody) at dilution 1/70. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to ANAPC15

货号：
P12975
别名：
APC15; HSPC020; C11orf51
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P60006
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to ANAPC15

Description
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

Description

ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.

Specification
Aliases	APC15; HSPC020; C11orf51
Swissprot	P60006
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human ANAPC15
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.