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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human lymph gland tissue lysate, Primary antibody: P12776(LAT Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12776(LAT Antibody) at dilution 1/30. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to LAT

货号：
P12776
别名：
LAT1; pp36
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Rat
抗体类型：
Primary antibody
Swissprot：
O43561
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to LAT

Description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Description

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specification
Aliases	LAT1; pp36
Swissprot	O43561
WB Predicted band size	28 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat
Immunogen	Synthetic peptide of human LAT
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.