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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: 293T, K562 and Raji cell, Primary antibody: P12560(DCX Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P12560(DCX Antibody) at dilution 1/35. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P12560(DCX Antibody) at dilution 1/35. (Original magnification: ×200)

Rabbit Polyclonal Antibody to DCX

货号：
P12560
别名：
DC; DBCN; LISX; SCLH; XLIS
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
O43602
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to DCX

Description
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

Description

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.

Specification
Aliases	DC; DBCN; LISX; SCLH; XLIS
Swissprot	O43602
WB Predicted band size	49 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human DCX
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.