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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: HepG2 cell, Human liver tissue, Mouse liver tissue, Human fetal liver tissue, LO2 cell lysates, Primary antibody: P12247(STARD4 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P12247(STARD4 Antibody) at dilution 1/50. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P12247(STARD4 Antibody) at dilution 1/50. (Original magnification: ×200)

Rabbit Polyclonal Antibody to STARD4

货号：
P12247
别名：
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q96DR4
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to STARD4

Description
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4.

Description

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4.

Specification
Swissprot	Q96DR4
WB Predicted band size	24 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human STARD4
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.