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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11965(NLRP4 Antibody) at dilution 1/30. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P11965(NLRP4 Antibody) at dilution 1/30. (Original magnification: ×200)

Rabbit Polyclonal Antibody to NLRP4

货号：
P11965
别名：
CT58; PAN2; RNH2; NALP4; PYPAF4; CLR19.5
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q96MN2
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to NLRP4

Description
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes

Specification
Aliases	CT58; PAN2; RNH2; NALP4; PYPAF4; CLR19.5
Swissprot	Q96MN2
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human NLRP4
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.